Byterna Raises Pre-Series A for In Vivo circmRNA CAR-T, Cancer Vaccines
2026-07-23
- China-based Byterna has closed a multimillion RMB Pre-Series A round with continued support from existing investor EFung Capital and new strategic participation from Insilico Medicine. Proceeds will accelerate clinical filing for BR101, a first-in-class dual-target circular mRNA (circmRNA) in vivo CAR-T candidate currently in investigator-initiated trials (IIT), fund an AI-driven personalised circmRNA tumour vaccine pipeline, and co-develop an AI-Native R&D engine with Insilico to integrate mRNA design, synthesis, and translational workflows.
- Founded in June 2023, Byterna specialises in next-generation RNA therapeutics combining the translational stability of circmRNA with AI-guided antigen prediction and sequence optimisation. BR101 aims to generate CAR-T cells directly inside the patient without ex vivo manipulation, potentially reducing manufacturing complexity and cost, whilst the vaccine programme targets a closed-loop, patient-specific design-to-synthesis pathway.
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